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The trial appeared in the Journal of the American Academy of Dermatology in December 2023, and it randomized 152 patients with moderate to severe acne to either 5-aminolevulinic acid photodynamic therapy or oral isotretinoin at 0.5 mg per kg per day

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The study was not designed or powered to look at efficacy for a specific condition, but treatment was noted to be safe.8,9 Dosing protocols or information regarding future human studies on MOTs-C or CB4211 are not currently available